Alzheimer’s Genes, The Four Known Alzheimer’s Genes

"Every new Alzheimer’s gene defect we find provides new clues regarding the cause of the disease, and what we need to do to stop the disease..."

Ultimately, the full list of Alzheimer’s genes emerging from the family-based genetic studies of the Alzheimer’s Genome Project and the population based studies of the International Genomics of Alzheimer's Project are getting us closer and closer to someday being able to eradicate Alzheimer’s disease using a strategy of early prediction and early intervention.
-- Dr. Rudolph Tanzi

Read it at the Alzheimer's Reading Room

First Comprehensive Gene Map of the Human Brain

Fascinating.

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It's being called the world's first "anatomically and genomically comprehensive" map of the human brain - a sort of "GPS for the brain" designed to speed research into brain disorders ranging from mental illness to Alzheimer's and Parkinson's diseases, autism, multiple sclerosis, and more...

"Until now, a definitive map of the human brain, at this level of detail, simply hasn't existed," the CEO of the Allen Institute for Brain Science, Dr. Allan Jones, said in a written statement, adding that the atlas gives "never-before-seen views into our most complex and most important organ." Read more at www.alzheimersreadingroom.com

 

Shut Up the Movie, Starring Dotty

Dotty is 94 years old. You might want to share this movie with your parents or grandparents.

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Dotty stars in her latest YouTube video -- Shut Up...

For those of you that are new. Dotty is 94 years old and has Alzheimer's. She was officially diagnosed in 2004.

Dotty was born in south Philadelphia in 1916. Dotty attended grammar school at Baldwin and Saint Monica's.

Feel free to add your review or comments

If you don't see the movie -- go here. Read more at www.alzheimersreadingroom.com

 

Dr Oz Eat Curry Prevent Alzheimer's Dise

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Dr.Oz's number one suggestion -- eat curry once or twice a week to help prevent Alzheimer's disease......

Dr Oz said:

Alzheimer's is a long slow death sentence.

In the future, either you get it, or know someone that has it (Alzheimer's). Read more at www.alzheimersreadingroom.com

 

Obama To Visit Facebook

Obama To Visit Facebook On April 20

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President Barack Obama will visit Facebook’s Palo Alto, Calif., headquarters on April 20 for a live-streamed conversation with the social network’s CEO Mark Zuckerberg, COO Sheryl Sandberg — and Facebook users who submit questions online.

The event is part of Facebook’s growing program of “Facebook Live” video streams, which feature Q&As with famous people and movers and shakers in the world of technology. Recent “Facebook Live” events with politicans include New York City Mayor Michael Bloomberg in October and former President George W. Bush in November. Read more at blogs.wsj.com

 

See this Amp at http://amplify.com/u/bxz0w

Alzheimers World -- The New Reality

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Once you accept Alzheimer's World and learn how to operate in Alzheimer's World you'll learn that opposites can indeed attract. And stick together like glue......

To understand Alzheimer's You must redefine reality This new reality is called Alzheimer's World

Imagine communicating with someone for 50 years or longer. Then they change. They are not the person you always knew? If not, then who are they? Who?

This person you always knew, starts acting and coping with the world in new and different ways. Strange, bizarre, unsettling ways. Many of these new behaviors make you angry, they drive you crazy, you feel out of sorts. You just can't understand.

You continue to try and make sense of what is happening in the way you always have. It doesn't work.

Every day, many times a day, you are at wits end. You don't know what to do. It's hopeless. Or is it?

You know that something needs to change. But discovering this change -- the what to do is elusive. You rack your brain. You just can't figure out what to do.

hen finally out of the nowhere -- the dark clouds separate. You see the light. You come to a conclusion that seems to be so simple.

Then finally out of the nowhere -- the dark clouds separate. You see the light. You come to a conclusion that seems to be so simple.

Something has to change and that something is YOU.

Communicating in Alzheimer's World Read more at www.alzheimersreadingroom.com

Researchers Link Herpes to Alzheimer's

Researchers Link Herpes to Alzheimer's disease

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Laboratories at the University of New Mexico (UNM), Brown University, and House Ear Institute (HEI) have developed a new technique to observe herpes simplex virus type 1 (HSV1) infections growing inside cells.

HSV1, the cause of the common cold sore, persists in a latent form inside nerve cells. Re-activation and growth of HSV1 infections contribute to cognitive decline associated with Alzheimer's disease. Read more at www.alzheimersreadingroom.com

New Genes Linked to Alzheimer's

Alzheimer's disease consortium identifies four new genes for Alzheimer's disease risk

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Largest study of its kind, researchers have identified four new genes linked to late-onset Alzheimer's disease, the most common form of dementia... Alzheimer's Reading Room

In the largest study of its kind, researchers have identified four new genes linked to late-onset Alzheimer's disease, the most common form of dementia...

In the largest study of its kind, researchers from a consortium led by the University of Pennsylvania School of Medicine, the University of Miami, and the Boston University School of Medicine, identified four new genes linked to Alzheimer's disease.

Each gene individually adds to the risk of having this common form of dementia later in life. These new genes offer a portal into what causes Alzheimer's disease and is a major advance in the field.

See more at www.alzheimersreadingroom.com

 

Biomarker for Tau Related Brain Disorder

New Biomarker for Tau Related Brain Disorders?

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Researchers at the University of Pennsylvania School of Medicine have determined that a well-known chemical process called acetylation has a previously unrecognized association with one of the biological processes associated with Alzheimer’s disease and related disorders. The findings were published in the latest issue of Nature Communications.

au is one of the primary disease proteins associated with a suite of neurodegenerative diseases. Tau proteins are expressed primarily in the central nervous system where they help with the assembly and sta

Tau is one of the primary disease proteins associated with a suite of neurodegenerative diseases. Tau proteins are expressed primarily in the central nervous system where they help with the assembly and stability of microtubules, protein structures that are the backbone of the nerve-cell communication system.

"As far as we know, almost all neurodegenerative diseases are characterized by the accumulation of misfolded proteins in the brain or spinal cord," Virginia M.-Y. Lee of the University of Pennsylvania. Read more at www.alzheimersreadingroom.com

 

The Plaid Pajamas and the Last Big Laugh

Teen reflects on the last big laugh from his grandmother who suffered from Alzheimer's disease.

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It was the last time I heard that laugh. Maybe it was the colorful plaids. Maybe it was how ridiculous Grandpa looked. Maybe it was because we all thought it was funny and she shared our emotions.....

That night, Grandpa put on his new wild and crazy pajamas and came downstairs. We all looked at him and started laughing. Great Grams was laughing the hardest. She was laughing her laugh of years before. She was laughing the laugh of who she really was. Read more at www.alzheimersreadingroom.com

 

Challenging Behavior in Persons with Dementia

Challenging Behavior in Persons with Dementia



This is an important article. Please share with families touched by Alzheimer's disease.

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The ONLY Way to Deal with Challenging Behavior in Persons with Dementia IS "To PREVENT IT in the First Place".....

This issue: challenging and violent behavior of Alzheimer's patients is important to all Alzheimer's caregivers. This thread was initiated by the this article -- Nobody Wants Our Dad

I have been working with this very vulnerable population, those with dementia and challenging/aggressive behavior, for the last 12 years.

After developing a model of specialized dementia care that has been successful in preventing the aggessive behavior in those that have had repeated discharges from other facilities and hospitalizations for behavior I have learned a few critical things I would like to share.

I'll start by saying I believe "NO One", the resident with the behavior, other residents, or staff should have to be subjected to violent behavior. We have learned that 90% of behavior can be contolled and/or eliminated by "pro-actively" Recognizing and Meeting the underlying need of the person displaying the behavior whether it be physical OR emotional. Read more at www.alzheimersreadingroom.com